Revolutionizing Endovascular Procedures with Advanced Micro-Technologies
Bio Micro Science develops groundbreaking micro-technologies to optimize the delivery of Cardiovascular and Cerebral treatments. Our solutions set new standards for precision, efficacy, and patient outcomes in endovascular procedures.
Key
Products
THE NINJA: An innovative low-profile crossing device combining a guidewire and inflatable balloon, streamlining treatment delivery in PTCA procedures.
THE SLIDER: A novel delivery system designed to effectively navigate cerebral tortuosity, enabling safe and precise access to challenging lesions.
OUR PARTNERS
ABOUT
At Bio Micro Science, we are at the forefront of medical innovations, developing cutting-edge devices for complex cardiac and neurovascular procedures. Our advanced technologies are designed to enhance precision, improve patient outcomes, and redefine the future of minimally invasive treatments.
OUR VISION IS
To lead the advancement of endovascular treatment delivery, improving patient care worldwide.
OUR MISSION
To engineer and deliver revolutionary micro-technologies that redefine the boundaries of precision and efficacy in endovascular procedures.
THE NINJA
The Ninja™: Advancing Percutaneous Transluminal Coronary Angioplasty (PTCA)
The Ninja is a groundbreaking low-profile crossing device that integrates a guidewire with an inflatable balloon. This unique combination streamlines PTCA procedures, making them faster and more accessible, even in complex and narrow lesions.
THE NINJA
An innovative low profile crossing device, uniquely combining a guide wire and an inflatable balloon, making the PTCA procedure fast and achievable, even in complex and narrow lesions
HOW DOES IT WORK
step 1-A
WIRE IN
The wire is thin enough to pass through the narrow lesion.
step 1-B
WIRE INFLATION
The wire itself is inflated, and act as a balloon to primarily widen the lesion
step 1-C
WIRE DENFLATION
The wire is deflated, and acts as a regular guidewire
step 2
CATHETER IN
step 3
stent placement
step 4
delivery
system out
aptery
opened
step 1-A
WIRE IN
The wire is thin enough to pass through the narrow lesion.
step 1-B
WIRE INFLATION
The wire itself is inflated, and act as a balloon to primarily widen the lesion
step 1-C
WIRE DENFLATION
The wire is deflated, and acts as a regular guidewire
step 2
CATHETER IN
step 3
stent placement
step 4
delivery
system out
aRtery
opened
The procedure follows and is completed as normal, delivering the stent to its place
FEATURES
0.3mm >> 1mm
UNPRECEDENTED
CROSSING PROFILE
Smallest in the world (0.3mm) with a burst strength (12atm), high flexibility and a low axial growth. Expands by 300% to reach a 1mm profile
IN LINE WITH THE PROCEDURE
Can be delivered via any 0.014” Micro catheter
‘NO-FOLD’ PROFILE
Constant dimensions along the tip/balloon transition
UNIQUELY PRODUCED
Providing strength
during inflation
PATENTED
TECHNOLOGY
Expanding Angioplasty treatment abilities
The NINJA 0.010” will game-change the current procedure, reducing treatment risks and costs:
SUPREME EFFICIANCY
Effortlessly challenges any type of blockage. No-surprises during the procedure, enables to deal with any finding
RISK REDUCTION
Reduces the incidences of bypass surgery, less morbidity, shorter recovery time
VERSATILE
In line with the procedure, enabling use of all kinds of stents and devices delivered over the wire
TIME SAVING
Fast, simple and easy to use. No need exchanging the guiding wire or starting over the procedure, reducing complexities and saving precious OP hours
REVOLUTIONARY TREATMENT
Patented technology, expanding Angioplasty treatment abilities
Developmental Milestones 510(k) device
Q2 2025
Finalizing development of 1st generation
Q2 2026
Finalization of Verification and Validations
Q4 2026
FIH
Q4 2027
Receive 510(k) clearance*
Q4 2025
POC in swine cardiac model and 510(k) Pre- submission to the FDA
Q4 2026
Finalization of swine cardiac model
Q2 2027
510(k) submission to the FDA
THE slider
The Slider™: Revolutionizing Cerebral Treatment Delivery
The Slider is a patented, innovative in-lumen sliding device designed to transform the delivery of treatments to the brain. Its unique mechanism minimizes friction, enabling easier navigation through tortuous arteries to reach challenging lesions.
THE slider
THE SLIDER is an innovative delivery system designed to navigate cerebral tortuosity and REACH CHALLENGING LESIONS, extracting them more effectively, in a faster and saver way, with fewer attempts.
A revolutionary novel cerebral
IN-LUMEN SLIDING device, developed to make delivery of treatment to the brain possible, easier and more successful
The device is designed to enable safe slide through the tortuous arteries, reducing risk, and allowing:
Enhanced Efficacy
Facilitates access to previously unreachable targets.
Efficient
Delivery
Ensures consistent force application with minimal power loss.
Simplified Procedure
Reduces the number of attempts and reliance on extensive skill.
Increased Safety
Minimizes friction and the risk of plaque debris, contributing to fewer complications.
Current Cerebral Treatments
HIGH RISK AND COMPLEX
The Current treatments involve High-risk emergent endovascular procedure, which is highly complicated to execute with significant adverse effects due to debris release that may cause strokes. The procedures demand high skills to perform successfully.
LIMITED ACCESS
through the narrow and tortuous carotid arteries, makes navigation extremely difficult, especially around the entry to the brain arteries through the CIRCLE OF WILLIS
SHORT TIME WINDOW
for effective treatment, enabling very few attempts to overcome the anatomy challenges and reaching the target and delivering treatment
FRICTION
of the delivery system against the brain artery-walls can
cause LOOSE PLAQUE DEBRIS falling into the blood stream causing serious complications and further strokes
STROKE STATISTICS
STROKE IS A LEADING CAUSE OF DEATH AND SERIOUS LONG TERM DISABILITY
1 IN 20
deaths in the united states are due to a stroke
EVERY 40 SECONDS
someone in the United States has a stroke.
~87%
of all strokes are Ischemic Strokes, in which blood flow to the brain is blocked
1 in 6 DEATHS
from cardiovascular disease was due to stroke
795,000 PEOPLE
Every year in the United States have a stroke.
$56.5 BILLION
Stroke-related costs in the United States
EVERY 3:14 MINUTES
someone dies of stroke
NEARLY 1 IN 4
are in people who have had a previous stroke
Stroke is a leading cause of serious long-term disability
A path to a better life
THE MARKET
THE NINJA
Cardiovascular Disease Statistics
- Cardiovascular disease is the world’s leading cause of death.
- Statistics on global deaths attributed to cardiovascular disease
- Challenges in PTCA procedures and the need for alternative solutions like The Ninja.
THE SLIDER
Stroke Statistics
- Stroke is a leading cause of death and long-term disability*.
- Statistics highlighting the prevalence and impact of stroke in the United States (e.g., deaths, cases per year, ischemic stroke percentage, costs).
- The limitations of current cerebral treatments (high risk, limited access, short time window, friction-related complications).
GUIDEWIRE MARKET SIZE
BY PRODUCT, 2020-2030 (USD MILLION)
Global Market CAGR, 2024 - 2030
WHO WE ARE
MANAGEMENT
Eli Ben Haroosh
CEO & Co-founder
Eli is a seasoned executive and entrepreneur with a proven track record of leading and growing successful businesses in various fields. He is the owner of several groundbreaking startups in the fields of drug delivery and medical devices with global patents. He also owns 2 public companies traded on stock exchanges around the world.
Dr. Asher Holzer
Director
Serial entrepreneur & senior executive with 30+ years in medical equipment. Proven track record founding, leading, and taking public multiple cutting-edge med-tech companies (e.g., UroGen, InspireMD). Holds a Ph.D. in Nuclear Physics (Hebrew University), driving innovation in healthcare.
Noam ShamaY
CTO & CO-Founder
Med-tech leader, inventor, and entrepreneur focused on innovation. Specializes in identifying opportunities & developing novel medical devices and technologies. Drives full lifecycle strategy including IP, Clinical, Regulatory, Technical, and Marketing.
Isaac Tal,
VP of Product Development
Experienced manager skilled in leading complex healthcare projects & strategic initiatives. Expertise spans operational leadership (led Tamarix), deal-making (Technion TTO), & med-tech/biotech investment ($100M Alfred Mann Inst. JV).
Holds a PhD in Physiology and an MBA from Hebrew University.
Eng. Yosh Dollberg
Senior VP Development & Engineering
Extensive industry experience: Traquat Urogen Pharma, VP AOI Orbotek (Computer Vision), Head of Medical systems Direx (shock
waves, MRI, γ radiation), VP Dev
Keulik & Sofa (SEMI industry),
Cubital (3D printing). >10 patents
and co-author on many peer-reviewed articles. B.Sc. Elec Engineering (Technion) M.Sc. Comp Engineering (BIU).
ADVISORY BOARD
A team of leading medical experts providing invaluable guidance.
Prof. Amit Segev
Chief advisory board
Interventional Cardiologist
Director, Division of Cardiology
The Heart Center Chaim Sheba Medical Center
President, Israel Heart Society
Prof of Cardiology, School of Medicine, Tel Aviv University
Dr. David Orion
Neuro endovascular and Head of Stroke & Neurovascular Department, Sheba Medical Center. My department specializes in brain vascular problems and IV thrombolysis for Stroke and Medications. We treat emergent stroke cases by Endovascular
Dr. Ricardo Krakover
Director of interventional cardiology Shamir Medical Center (Retired)
Faculty of Sacker School of Medicine Tel Aviv (Retired)
PI in multicenter Investigation Director of Cardiac Catheterization Unit (ex- Argentina)Performed about 14000 Cardiac and peripheral procedure
MEDIA & INVESTORS
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